
BA 1
CAS No. 183241-31-8
BA 1 ( —— )
产品货号. M30733 CAS No. 183241-31-8
Potent bombesin receptor agonist (IC50 values are 0.26, 1.55 and 2.52 nM for BB1, BB2 and BB3 respectively). Enhances glucose transport in obese and diabetic primary myocytes. Also stimulates NCI-H1299 lung cancer cell proliferation in vitro.
纯度: >98% (HPLC)






规格 | 价格/人民币 | 库存 | 数量 |
100MG | 获取报价 | 有现货 |
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200MG | 获取报价 | 有现货 |
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500MG | 获取报价 | 有现货 |
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生物学信息
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产品名称BA 1
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注意事项本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
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产品简述Potent bombesin receptor agonist (IC50 values are 0.26, 1.55 and 2.52 nM for BB1, BB2 and BB3 respectively). Enhances glucose transport in obese and diabetic primary myocytes. Also stimulates NCI-H1299 lung cancer cell proliferation in vitro.
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产品描述Potent bombesin receptor agonist (IC50 values are 0.26, 1.55 and 2.52 nM for BB1, BB2 and BB3 respectively). Enhances glucose transport in obese and diabetic primary myocytes. Also stimulates NCI-H1299 lung cancer cell proliferation in vitro.
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体外实验BA 1 (0.1 μM) significantly increases FAK tyrosine phosphorylation in BRS-3 transfected NCI-H1299 cells.
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体内实验——
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同义词——
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通路GPCR/G Protein
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靶点Bombesin Receptor
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受体——
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研究领域——
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适应症——
化学信息
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CAS Number183241-31-8
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分子量1133.32
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分子式C57H76N14O11
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纯度>98% (HPLC)
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溶解度water:2 mg/mL
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SMILES[H]N[C@H](CC1=CC=C(O)C=C1)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC1=CNC2=C1C=CC=C2)C(=O)N[C@@H](C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](CC1=CNC=N1)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CCCC)C(N)=O
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1. González et al (2015) Effect of bombesin receptor subtype-3 and its synthetic agonist on signaling, glucose transport and metabolism in myocytes from patients with obesity and type 2 diabetes Int.J.Mol.Med. 35 925 PMID: